Input sequence shorter than 25 nt is not allowed and input sequence longer than nt will be truncated from most 3' closer to start codon to 5'. The most negative log2-transformed fold change value, together with the SNV's position and mutation is shown in blue, and this means that the SNV brings the biggest effect on decreasing MRL for the input sequence. Use chromosome coordinate from GRCh38 to find out input sequence.
Click on 'Search' to trigger inquiry. Resulting sequence will be shown in the large type-in box. Search for gene of interest in the dropdown menu and pick the specific transcript ID from that gene. Press 'Predict' button to generate prediction including MRL value and in-silico saturation mutagenesis. Filter on SNVs' Scores. Select the direction of filtering first, and type in the threshold value. For example, if 'higher than' was selected, and '0' was put in as the threshold value, press 'Filter' button, then the list of SNVs containing position and mutation information, which produce log2-transformed fold change value higher than 0, will pop up in the box below.
The list order is sorted by fold change in default. It would then have to fall back upon the imperial title without specifically naming its holder R. Report an error Linked Data. Share on. Have you found a typo, mistake, or other error on this page? Help us improve RIB by letting us know. Please indicate where the error occurs and provide as much detail as you can. If possible, please also provide citations supporting your assertion.
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